Physiological Integrity

Pharmacological and Parenteral Therapies

Administration, expected effects, adverse reactions, antidotes and blood products.

In short

Pharmacological and Parenteral Therapies accounts for 13–19% of NCLEX-RN items. It sits under Physiological Integrity in the test plan. Administration, expected effects, adverse reactions, antidotes and blood products. Percentages are ranges: an individual exam may differ by up to ±3% in each category.

Where it sits

In the test plan
CategoryPhysiological Integrity
Share of the exam13–19%
Variation allowedup to ±3% on an individual exam

How it is tested

Every Pharmacological and Parenteral Therapies item is also tagged to a step of clinical judgment, because the category tells you WHAT is being asked about and the step tells you what kind of thinking is being asked for. A pharmacological and parenteral therapies item at recognize cues and one at take action are different tasks on the same subject.

1
Recognize cuesWhat matters here?

Sorting the relevant from the noise in a patient picture that contains both.

2
Analyze cuesWhat could it mean?

Linking findings to what would explain them, and to what they rule out.

3
Prioritize hypothesesWhat matters MOST?

Ranking by urgency and risk — the step where most "I knew that" answers are lost.

4
Generate solutionsWhat can I do?

Naming the actions that would address the priority, before choosing between them.

5
Take actionWhat will I do first?

Choosing and sequencing — the largest share of the bank, and of the exam.

6
Evaluate outcomesDid it work?

Reading the response to the intervention, and deciding whether to continue or change.

What that means for how you practise it

  • Volume alone will not move this category. 13–19% of the exam is a meaningful share, but items are lost at a specific reasoning step, and that step is what the practice has to target.
  • Work it against the clock at least sometimes. Every category is tested under the same time pressure as the rest.
  • Read the rationale on the ones you got right. A correct answer reached by the wrong route is a wrong answer that has not happened yet.

The whole blueprint, for comparison

Safe and Effective Care Environment
Management of Care15–21%
Safety and Infection Prevention and Control10–16%
Health Promotion and Maintenance
Health Promotion and Maintenance6–12%
Psychosocial Integrity
Psychosocial Integrity6–12%
Physiological Integrity
Basic Care and Comfort6–12%
Pharmacological and Parenteral Therapies13–19%
Reduction of Risk Potential9–15%
Physiological Adaptation11–17%

Ranges, not points — an individual exam may differ by up to ±3% in each category. Source: 2026 NCLEX-RN Test Plan (NCSBN).

Every category in detail: the Client Needs pages. How the exam measures reasoning across all of them: the six-step model.

Practise where your reasoning actually breaks

Every item is tagged to the step of clinical judgment it tests, so the report says where it went wrong — not just how many.

Start free

Frequently asked questions

What percentage of the NCLEX is Pharmacological and Parenteral Therapies?

13–19% of items, as published in the 2026 NCLEX-RN Test Plan. An individual exam may differ by up to ±3%.

What does Pharmacological and Parenteral Therapies cover?

Administration, expected effects, adverse reactions, antidotes and blood products.

Where does it sit in the test plan?

Under Physiological Integrity.

Sources

Exam facts checked against the 2026 NCLEX-RN Test Plan on 30 August 2026.

By PrepScore · Last reviewed · Editorial standards